[Nanosafety studies of nanomaterials about biodistribution and immunotoxicity].

Data Mining as a Guide for the Construction of Cross-Linked Nanoparticles with Low Immunotoxicity via Control of Polymer Chemistry and Supramolecular Assembly.

The potential immunotoxicity of nanoparticles that are currently being approved, in different phases of clinical trials, or undergoing rigorous in vitro and in vivo characterizations in several laboratories has recently raised special attention. Products with no apparent in vitro or in vivo toxicity may still trigger various components of the immune system unintentionally and lead to serious ad...

Evaluating Nanosafety of Nanomaterials by In-vitro Cytotoxicity Tests on Fibroblast Cells

In the recent years, the use of nanomaterials has increased exponentially. In spite of the extensive research in this field, some areas are not completely understood, one of them being nanosafety. Because of their size and shapes, these nanomaterials have the ability to be easily absorbed in the biological and the ecological systems and interfere with them by hampering smooth functioning. In th...

Editorial: Interaction of Nanomaterials with the Immune System: Role in Nanosafety and Nanomedicine

High dispersity of carbon nanotubes diminishes immunotoxicity in spleen

BACKGROUND From the various physiochemical material properties, the chemical functionalization order of single-walled carbon nanotubes (swCNTs) has not been considered as a critical factor for modulating immunological responses and toxicological aspects in drug delivery applications. Although most nanomaterials, including carbon nanotubes, are specifically accumulated in spleen, few studies hav...

The need for in situ characterisation in nanosafety assessment: funded transnational access via the QNano research infrastructure

The first concerns regarding potential toxicities of nanomaterials were raised almost 10 years ago, as fears that the small size of nanoparticles might allow them unique access to organisms, cells, cellular barriers and subcellular organelles with potentially harmful consequences resulting from quantum properties (Colvin 2003). Much has been learned in the intervening period, and indeed nanosaf...